METHODS: Data from 2 cohorts of patients with first episode psychosis … Studies have shown that the earlier treatment is initiated for psychosis, the better the long-term outcomes for the patient. In general, research has shown that treatments for psychosis work better when they are delivered closer to the time … Duration of untreated psychosis has a significant effect on treatment adherence in the initial recovery phase. Delay in intensive psychosocial treatment (DIPT) may also be related to outcome. DUP is generally determined as the time from the onset of psychotic symptoms to the initiation of treatment or first clinical presentation, when a diagnosis of first-episode psychosis may be given. An extended duration of untreated psychosis (DUP) is associated with poor outcome in first-episode psychosis (FEP). To assess the impact of duration of untreated psychosis (DUP) on baseline and 18-month follow-up characteristics controlling for relevant confounders in an epidemiological first-episode psychosis (FEP) cohort.The Early Psychosis Prevention and AB - Duration of untreated psychosis (DUP) is the time from manifestation of the first psychotic symptom to initiation of adequate treatment. Pharmacological management of first-episode schizophrenia and related nonaffective psychoses. AIM: Duration of untreated psychosis (DUP) is considered as a key prognostic variable in psychosis. The authors reviewed the literature on the association of duration of untreated psychosis with symptom severity at first treatment contact and with treatment outcomes and conducted a meta-analysis examining these relationships. This study examined outcome and factors related to it after one year of treatment of schizophrenia patients who were ill for many years and not previously treated. Relationship between duration of untreated psychosis and outcome in first-episode schizophrenia: a critical review and meta-analysis. Figure 1 shows the differences in access to mental 2 The Canadian Journal of Psychiatry -To reduce duration of untreated psychosis (DUP), which has been associated with worse outcomes … DUP is generally determined as the time from the onset of psychotic symptoms to the initiation of treatment or first clinical presentation, when a diagnosis of first-episode psychosis may be given. by Marshall and colleagues (2) of DUP and outcomes among patients with FEP. Bradford DW, Perkins DO, Lieberman JA. Psychosis is one of the most debilitating psychiatric conditions with limited options to improve outcomes. This study examined outcome and factors related to it after one year of treatment of schizophrenia patients who were ill for many years and not previously treated. Untreated psychosis has long been associated with worse clinical outcomes in patients with schizophrenia. 2005;162(10):1785-1804. If so, outcome might be improved through earlier detection and treatment. For over a decade, the DUP has been studied as a potential predictor of a variety of outcomes. Arch Gen Psychiatry 2005;62:975–83. The duration of untreated psychosis, or DUP, is measured as the time from the beginning of psychotic symptoms to the time a person starts treatment for those symptoms or a diagnosed condition. Previous studies have associated a longer DUP with a poor prognosis, but few of them were performed in countries with low and middle level of income. We searched electronic databases and conducted forward … OBJECTIVE The duration of untreated psychosis may influence response to treatment, reflecting a potentially malleable progressive pathological process. U2 - 10.1001/archpsyc.62.9.975. A: The length of time between the start of psychotic symptoms and the beginning of treatment is called the duration of untreated psychosis or DUP. Yet, it is unclear whether a longer DUP causes worse outcomes or whether reported associations have alternative explanations. We systematically reviewed the literature on racial and ethnic differences in DUP in patients with FEP. Duration of untreated psychosis and outcomes What is duration of untreated psychosis (DUP)? 45 Studies, primarily performed in high-income countries in which the duration of untreated psychosis is usually less than 5 years, have reported that a longer duration of untreated psychosis is associated with more severe positive and negative symptoms and lower rates of … 1 One key strategy is reducing the duration of untreated psychosis (DUP), the time from the first symptom of psychosis to the start of treatment. OBJECTIVE: The duration of untreated psychosis may influence response to treatment, reflecting a potentially malleable progressive pathological process.The authors reviewed the literature on the association of duration of untreated psychosis with symptom severity at first treatment contact and with treatment outcomes and conducted a meta-analysis examining these relationships. Association between duration of untreated psychosis and in cohorts of first-episode outcome patients: a systematic review. Duration of untreated psychosis (DUP) is the time between onset of psychotic symptoms and initiation of antipsychotic medication. 2 Accumulating studies have shown that a longer DUP is associated with poorer outcomes for people with first-episode psychosis (FEP), … Download Duration of Untreated Psychosis (DUP) Measurement by Jo Smith. Duration of untreated psychosis (DUP) is one of the few potentially modifiable outcome predictors in psychosis. 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